The classical view that the cerebellum is solely implicated to motor control has long been discarded22; with evidence from several studies involving healthy individuals and patients with cerebellar lesions, indicating the involvement of the cerebellum in cognition and emotion23,24. In the context of these evidences, the finding of associations between FC and education level are not particularly unexpected; here, the intriguing finding concerns the fact that these are negative associations. However, when looking at the mean FC of this network, it can be observed that in absolute values it is actually positively associated with years of education (meaning that increased education level is associated with increased anti-correlations ,in this network, rather than the loss of FC). Given that there is evidence for the differential involvement of the cortex and the cerebellum and for education to modulate this functional balance25, it is hypothesized that this negative association does not reflect a negative impact but rather a more effective involvement of the cerebrum and cerebellum through this network. A major limitation of the present study is its Inteligen advanced brain formula cross-sectional design. A longitudinal approach would enable the within-subject analysis of the effect of aging, thus reducing inter-individual variability.
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